Non‐ mRNA 3′ end formation: how the other half lives
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چکیده
منابع مشابه
Non-mRNA 3' end formation: how the other half lives.
The release of nascent RNA from transcribing RNA polymerase complexes is required for all further functions carried out by RNA molecules. The elements and processing machinery involved in 3' end formation therefore represent key determinants in the biogenesis and accumulation of cellular RNA. While these factors have been well-characterized for messenger RNA, recent work has elucidated analogou...
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The nucleotide (nt) sequence of the 3' end of the yeast HIS3 mRNA was determined by PCR amplification of the 3' end. Analysis of 28 individual clones revealed that at least 13 distinct polyadenylation sites are present. The sites of polyadenylation are extremely heterogeneous and do not show any obvious similarity other than that they occur after pyrimidine residues in most cases. Most mutants ...
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ژورنال
عنوان ژورنال: WIREs RNA
سال: 2013
ISSN: 1757-7004,1757-7012
DOI: 10.1002/wrna.1174